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51.
We compared quantitatively vinculin-related adhesion parameters in osteoblastic cells submitted to opposite mechanical stresses, i.e., low deformation and frequency strain regimens (stretch condition) and microgravity exposure (relaxed condition). Cyclic deformation induced a biphasic response comprising new focal contacts formation followed by their clustering in ROS cells. Microgravity exposure induced a reduction in focal contact number and clustering in ROS cells. We previously demonstrated that 1% cyclic deformations at 0.05 Hz during a daily 10 min episode over 7 days stimulated ROS 17/2.8 growth as compared to static culture whereas relaxed ROS proliferated similarly to static culture (BC). To evaluate whether the proliferation (stretch) or the survival (relaxed) status of ROS cells influences focal contact organization, we inhibited ERKs proliferative-dependent pathway. Inhibition of proliferation by PD98059 was overcome although not fully restored by stretch. Furthermore stretch-induced clustering of vinculin-positive contacts still occurs in the presence of ERKs inhibitor, whereas the increase in focal contact number is abolished. In conclusion, we showed that focal contacts are mechanoeffectors and that hyper-mechanical stimulation could up regulate focal contacts size as compared to hypo-mechanical that down regulate clusterization.  相似文献   
52.
Space technology plays a pivotal role in society development. It offers new methods for telemetry, monitoring and control. However, this sector requires training, research and skills development but the lack of instruments, materials and budgets affects the ambiguity to understand satellite technology. The objective of this paper is to describe a demonstration prototype of a smart phone device for space operations study. Therefore, the first task was carried out to give a demonstration for spatial imagery and attitude determination missions through a wireless communication. The smart phone’s Bluetooth was used to achieve this goal inclusive of a new method to enable real time transmission. In addition, an algorithm around a quaternion based Kalman filter was included in order to detect the reliability of the prototype's orientation. The second task was carried out to provide a demonstration for the attitude control mission using the smart phone’s orientation sensor, including a new method for an autonomous guided mode. As a result, the acquisition platform showed real time measurement with good accuracy for orientation detection and image transmission. In addition, the prototype kept the balance during the demonstration based on the attitude control method.  相似文献   
53.
Global dependence on the space sector is increasing rapidly. However, the growing challenges outer space poses to international security have not, as yet, been effectively addressed in the United Nations Conference on Disarmament (CD) or in other multilateral fora. This paper briefly reviews the current state of affairs of international security and outer space and explores the challenges the international community faces in building international agreements for improved space security and global stability. It examines some of the hurdles that are faced in tackling space security issues are and provides some thinking on ways to overcome them. The paper concludes that there is a potential role for the disarmament community and the CD in particular. As potential conflicts in outer space emerge, having invested bodies and communities such as the CD and a strong cadre of disarmament diplomats and NGOs to act as an informed hub on space and disarmament issues is essential.  相似文献   
54.
伪多源采样复域FastICA冲击定位算法   总被引:2,自引:2,他引:0  
使用传感器阵列对材料结构冲击损伤进行定位,有助于及时发现损伤及潜在威胁,保障结构安全性。采用盲源分离(BSS)对传感器阵列信号进行预处理,提出单通道伪多源采样方法,利用每个传感器的分时段信息构建该传感器多源观测信号作为复域FastICA算法的输入,分离出每个传感器观测到的带有相位信息的冲击信号;结合阈值时延定位方法求解平面冲击事件的坐标。理论推导和数值仿真验证了本文设计的联合冲击定位算法的有效性。冲击定位平台上的实验结果表明,联合冲击定位算法可以从冲击-振动混合信号中分离出冲击信号,提高阵列传感器冲击定位的时延分析准确性。同时对传感器数量少于源信号的欠定BSS问题提供了一种解决方案。   相似文献   
55.
杜楠楠  陈建  马奔  王术波  张自超 《航空学报》2021,42(6):324476-324476
为解决传统电动无人机在覆盖作业时存在的续航时间短的问题,提出应用多架太阳能无人机进行覆盖作业。首先,在建立了应用于覆盖作业的太阳能无人机的能量模型的基础上,提出了能量流动效率这一指标来评价太阳能无人机在作业过程中对能量的利用率。其次,针对边界存在障碍物的凹多边形区域和内部含障碍物的多边形区域,以总作业完成时间最短为优化目标,提出基于无向图搜索方法的覆盖路径优化模型,定义约束方程限制无人机按照一定规则访问无向图中的节点,通过混合整数线性规划的方法求解每架无人机的最优飞行路径。再次,考虑无人机转弯时的姿态变化对能量流动效率的影响,将总作业完成时间最短和总能量流动效率最高同时作为优化目标,建立双目标优化方程,在首先以作业时间最短为优化目标进行求解的基础上,通过有限遍历的方式选择使能流效率和作业时间相对最优的覆盖飞行方向及飞行路径。大量仿真实验表明,所提的优化模型选取不同的优化目标,应用于不同形状的待覆盖区域,适用性广,在工程上应用范围广、可行性强。  相似文献   
56.
飞机燃油测量传感器优化布局技术   总被引:1,自引:1,他引:0  
实时、准确地测量出飞机各油箱的剩余油量,对飞机飞行安全十分重要.为了提高飞机燃油的测量精度,设计了一种基于粒子群算法(PSO)的燃油测量传感器优化布局方法.首先,引入燃油实体的概念,建立了某机翼复杂、带隔断多腔油箱CAD模型及箱内燃油实体模型;其次,基于Unigraphics NX(UG)二次开发,完成了飞机不同姿态下、复杂不规则多腔油箱燃油体积的解算;再次,提出了飞机油箱最大燃油可测区(LMR)的概念,并以此作为优化目标进行传感器优化布局;最后,引入可设置边界距离因子(BDF),解决了传感器布局时与油箱壁距离过近的问题.结果表明,该方法实现了多根燃油传感器的布局,可以不受油箱形状和大小的限制,有效避开了油箱内部的干涉区域,保证不同飞行姿态下油量测量的连续性,并使得飞机燃油的可测范围达到较高水平.   相似文献   
57.
The system worth or cost effectiveness concept covers the measure of a system in terms of total dollar value. System worth encompasses the elements of system effectiveness (a quantitative measure of a system's technical ability) as well as cost. One of the elements of system effectiveness is maintainability. Maintainability is an effective mechanism for the accomplishment of planned maintenance during the early design and development phases of a system. Planned maintenance is an element of integrated logistics support. The intent of this paper is to outline the basic elements associated with system worth, system effectiveness, and integrated logistics support, to outline the interrelation-ships of these concepts, and to cover the discipline of maintainability as an element of each concept.  相似文献   
58.
针对空空导弹捷联惯导系统传递对准的精度和快速性之间的矛盾,设计一种利用弹载北斗卫星导航信息的捷联惯导系统飞行中对准算法,详细推导了惯性系下基于北斗卫星伪距/伪距率的飞行中对准模型,优化了飞行中对准的量测方程,对北斗卫星接收机的钟差和钟漂进行了降维处理.相应的数学仿真试验结果表明,所提算法能够在飞行过程中实现捷联惯导系统的初始对准,在10s内对准精度优于6',同时该算法通过在线标定惯性传感器随机启动误差,能够提高捷联惯导系统导航精度和导弹系统抗干扰能力.  相似文献   
59.
机会数字阵雷达是以平台隐身性设计为核心,以数字阵列雷达为基础,兼具多功能、多模式的"一体化"新概念雷达系统.本文在对国外有关概念雏形描述理解基础之上,对其定义和涵义进行了深入透析,详细论述了"机会"一词的几层涵义.分析了机会数字阵雷达不同于传统相控阵雷达的技术特性和应用潜力,以及机会数字阵雷达所面临的技术难题,如3-D空间单元"机会性"分布优化选取和波束综合,信号传输与同步以及多自由度的系统资源优化管理等问题,并给出了初步的解决方案和仿真结果.  相似文献   
60.
一类冗余星载惯性姿态参考系统的可靠性分析   总被引:2,自引:0,他引:2  
随着航天事业的发展 ,对航天器的长寿命提出越来越高的要求 ,需要简便可行的冗余方案以备工程所需。文中提出一种对于混合冗余系统的可靠性研究的计算方法。并将这种方法应用到星载惯性姿态参考基准上 ,提出了一种有别于常规冗余方案 (工作冗余加N中取K系统和N中取K加冷储备系统 )的新方案 ,为工程实现作了理论上准备  相似文献   
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